karpowicz_lab_monogram_only_white@2

Publications

2018

Intestinal stem cells exhibit con­di­tional cir­ca­dian clock function. K. Parasram, N. Bernardon, M. Hammoud, H. Chang, L. He, N. Perrimon, P. Karpowicz. Stem Cell Reports 11(5): 1287 – 1301 (2018).

Circadian clock function occurs in a tissue‐specific manner in Oncorhynchus tshawytscha. M. Thraya, M. Hammoud, S. Rao, T. Pitcher, D. Heath, P. Karpowicz. (in prepa­ra­tion)

2017

Stokes, K., Cooke, A., Chang, H., Weaver, D.R., Breault, D.T., Karpowicz, P. The cir­ca­dian clock gene BMAL1 coor­di­nates intesti­nal regen­er­a­tion. Cellular & Molecular Gastroenterology and Hepatology 4(1): 95 – 114 (2017).

2015

Amin, R., Karpowicz, P., Carey, T.E., Arbiser, J., Nahta, R., Chen, Z.G., Dong, J‐T., Kucuk, O., Khan, G.N., Huang, G.S., Lee, H‐Y., Reichrath, J., Honoki, K., Georgakilas, A.G., Amedei, A., Amin, A., Helferich, B., Boosani, C.S., Ciriolo, M.R., Chen, S., Mohammed, S.I., Azmi, A.S., Keith, W.N., Bhakta, D., Halicka, D., Niccolai, E., Fujii, H., Aquilano, K., Ashraf, S.S., Nowsheen, S., Yang, X., Bilsland, A, Shin, D.M. Evasion of anti‐growth sig­nal­ing: a key step in tumori­ge­n­e­sis and poten­tial target for treat­ment and pro­phy­laxis by natural com­pounds. Seminars in Cancer Biology 35: S55‐77 (2015).

Block, K.I., et al. Designing a broad‐spectrum inte­gra­tive approach for cancer pre­ven­tion and treat­ment. Seminars in Cancer Biology 35: S276‐304 (2015).

2013

Karpowicz, P., Zhang, Y., Hogenesch, J.B., Emery, P., Perrimon, N. The cir­ca­dian clock gates the intesti­nal stem cell regen­er­a­tive state. Cell Reports 3(4): 996‑1004 (2013).

DeVeale, B., Bausch‐Fluck, D., Seaberg, R., Runciman, S., Akbarian, V., Karpowicz, P., Yoon, C., Song, H., Zandstra, P., Wollscheid, B., van der Kooy, D. Surfaceome pro­fil­ing reveals reg­u­la­tors of neural stem cell function. Stem Cells 32(1): 258 – 68 (2013).

2011

Smukler, S.R., Arntfield, M.E., Razavi, R., Bikopoulos, G., Karpowicz, P., Seaberg, R., Dai, F., Lee, S., Ahrens, R., Fraser, P., Wheeler, M., van der Kooy, D. The Adult Mouse and Human Pancreas Contain Rare Multipotent Stem Cells that Express Insulin. Cell Stem Cell. 8(3): 281 – 93. (2011).

Ni, J.Q., Zhou, R., Czech, B., Liu, L., Holderbaum, L., Yang‐Zhou, D., Shim, H.S., Tao, R., Handler, D., Karpowicz, P., Binari, R., Booker, M., Brennecke, J., Perkins, L.A., Hannon, G.J., Perrimon, N. A Genome‐Scale shRNA Resource for Transgenic RNAi in Drosophila. Nature Methods. 8(5): 405 – 7. (2011).

2010

Karpowicz, P., Perez, J., Perrimon, N. The Hippo Tumor Suppressor Pathway Regulates Intestinal Stem Cell Regeneration. Development 137(24): 4135 – 45 (2010).

Karpowicz, P., Perrimon, N. All for One and One for All: The Clonality of the Intestinal Stem Cell Niche. F1000 Biology Reports 2:73 (2010).

Karpowicz, P., Biased DNA Segregation. Encyclopedia of Life Sciences. John Wiley & Sons, Ltd: [DOI: 10.1002/9780470015902.a0022543] (2010).

Karpowicz, P., Response to Letter from Renata Maas. DNA Repair. 9: 1024 – 25 (2010).

2009

Karpowicz, P., Willaime‐Morawek, S., Inoue, T., Deveale, B., Hitoshi, van der Kooy, D. E‐Cadherin Regulates Neural Stem Cell Self‐Renewal. Journal of Neuroscience. 29(12): 3885 – 96. (2009).

Karpowicz, P., Pellikka, M., Godt, D., Tepass, U. The germline stem cells of Drosophila melanogaster par­ti­tion DNA non‐randomly. European Journal of Cell Biology. 88(7): 397 – 408. (2009).

2008

Coles‐Takabe, B.L., Brain, I., Purpura, K.A., Karpowicz, P., Zandstra, P.W., Morshead, C.M., van der Kooy, D. Don’t Look: Growing clonal versus non‐clonal neural stem cell colonies. Stem Cells. 26(11): 2938 – 44. (2008).

2007

Karpowicz, P., Inoue, T., Runciman, S., Chaddah, R., Seaberg, R., Gertsenstein, M., Byers, L., Yamanaka, Y., Tondat, S., Slevin, J., Hitoshi, S., Rossant, J., van der Kooy, D. Adhesion Is Prerequisite But, Alone, Is Insufficient for Neural Stem Cell Pluripotency. Journal of Neuroscience. 27(20): 5437 – 47. (2007).

2005

Karpowicz, P., Morshead, C., Kam, A., Jervis, E., Cheng, V., van der Kooy, D. Support for the Immortal Strand Hypothesis: Neural Stem Cells Partition DNA Asymmetrically in vitro. Journal of Cell Biology. 170(5): 721 – 32. (2005).

Karpowicz, P., Cohen, C., van der Kooy, D. Developing Human/Nonhuman Chimeras in Human Stem Cell Research: Ethical Issues and Boundaries. Kennedy Institute of Ethics Journal. 15(2): 107 – 34. (2005).

2004

Karpowicz, P., Cohen, C., van der Kooy, D. It is Ethical To Transplant Human Stem Cells into Nonhuman Embryos. Nature Medicine. 10(3): 331 – 5. (2004).

Stewart, J.M., Blakely, J.A., Karpowicz, P., Martin, B.M., Thatcher, B. Unusually weak oxygen binding, physical prop­er­ties, partial sequence, autox­i­da­tion rate and a poten­tial phos­pho­ry­la­tion site of beluga whale (Delphinapterus leucas) myo­glo­bin. Comp Biochem Physiol B Biochem Mol Biol. 137(3): 401 – 12. (2004).

2003

Karpowicz, P. In Defense of Stem Cell Chimeras: A Response to ‘Crossing Species Boundaries’. American Journal of Bioethics. 3(3): w17‐19. (2003).